Prost-P10x® Ingredients and Clinical Studies

Extra Strength Natural Ingredients

Research Based, Proven Clinical Trials, Patented Formulas, Therapeutic Dosages

Graminex Pollen Extract (G63™)

Meriva^® Curcumin Phytosome

Saw Palmetto Extract

Quercetin Dihydrate

Beta-sitosterol

Green Tea Extract

Vitamin D-3

(DIM) 3,3-
Diindolylmethane

Cranberry

Stinging Nettle

Pygeum africanum

Zinc

Graminex (G63™) flower pollen extract (500mg) (Secale cereal L., containing fat and water soluble fractions in a 20:1 ratio): Graminex (G63™) rye pollen in Prost-P10x has been used for 35 years in Europe for prostatitis, BPH and to support healthy prostate volume and normal nighttime urination. Unlike other pollen formulas which can lack consistency in source and quality, the Graminex in Prost-P10x is a standardized blend of (Secale cereal), corn pollen (Zea mays), and timothy pollen (Phleum pretense) which has shown success in several double-blind clinical studies to support overall prostate health.

European Urology published a randomized, multicenter, double-blind, placebo-controlled phase 3 study showing significant improvements in total symptoms related to prostate health, including comfort and overall quality of life. Eur Urol 2009 Sep; 56(3): 544-51

Double-blind, placebo-controlled study published in the British Journal of Urology.Cernilton had a beneficial effect on prostate health and may help promote peak urine flow. Br J Urol 1990; 66(4):398-404

Published Study in Urology: Pollen extract provided support for prostate health. Urology 2006 Jan; 67(1): 60-63

Meriva^® Curcumin Phytosome (160mg) (Curcuma longa extract, rhizome): Studies have shown that curcumin, a naturally occurring biologically active group of compounds from Curcuma longa (turmeric), can function as efficient antioxidants and can help regulate the body’s normal response to inflammatory processes. Curcumin can also play an important role in maintaining healthy angiogenic balance and help to support the body’s detoxification processes. Prostate Research Labs uses a highly bioavailable curcumin called Meriva^® which has been shown to have up to a 20-fold improvement in bioavailability versus the standard 95% turmeric extracts.

International Journal of Antimicrobial Agents. A combination of curcumin, quercetin, saw palmetto, and stinging nettle was given to men who had prostatitis. Researchers reported that compared with men who received an antibiotic alone, those who took the herbal combination along with the antibiotic had significantly better resolution of their symptoms. Cai T et al: results from a prospective randomized study. Int J Antimicrob Agents 2009 Jun; 33(6): 549-53

Published Studies show curcumin to be effective in managing chronic nonbacterial prostatitis. Researchers believe curcumin is beneficial because it reduces the effect of the pro-inflammatory cytokines interleukin-8 and tumor necrosis factor alpha in the blood and tissues. Zhang QY et al. Reducing effect of curcumin on expressions of TNF-alpha, IL-6 and IL-8 in rats with chronic nonbacterial prostatitis. Zhonghua Nan Ke Xue 2010 Jan; 16(1): 84-88

Columbia University Study: Researchers noted the benefits that turmeric provided in support of prostate health in patients. Dorai T et al. Therapeutic potential of curcumin in human prostate cancer. Prostate Cancer Prostatic Dis 2000 Aug; 3(2): 84-93

Saw Palmetto Extract (640mg): The combined 640mg of saw palmetto (45% Fatty Acids) in Prost-P10x has been shown to be the most effective in studies in boosting prostate health and promoting a healthy libido.

A summary of the studies relating to Saw Palmetto demonstrate the benefits of the 640mg, 45% fatty acid content in Prost-P10x particularly when used with the stinging nettle, quercetin, and curcumin combination in Prost-P10x.

Published results in Urology International – Statistically significant improvement in prostate health, quality of life, sexual function and reduction in residual urinary volume and prostate volume. Urol Int 2011

Clinical trial reported in Advances in Therapy – Multi-center clinical trial. The results showed that urinary and prostate health were promoted in the supplement group versus the placebo group. The researchers also reported that the prostate health-promoting activity of saw palmetto was quite significant. Adv Ther 2010 Aug; 27(8): 555-63*

A double-blind trial published in European Urology in 2002 indicated that saw palmetto is effective in promoting normal prostate size. Eur Urol 2002; 41(5):497-506.

The International Journal of Antimicrobial Agents reported on a prospective, randomized study in which 89.6 percent of men who received a combined herbal formula of saw palmetto, stinging nettle, quercetin and curcumin saw their prostate health increase significantly after the trial. Int J Antimicrob Agents 2009 Jun; 33(6): 549-53

Quercetin Dihydrate (500mg): (flavonoid complex) Quercetin is a flavonoid found in many plants and foods, most notably red grapes, red wine, apples, tea, berries, and onions. For more than a decade, quercetin has been recognized as a potent antioxidant as well as being beneficial in supporting overall prostate health, usually at a dose of 500 mg daily. Quercetin has demonstrated in studies to provide symptomatic relief particularly when used with a saw palmetto and quercetin combination similar to that found in Prost-P10x.

Randomized, double-blind study published in Urology - 500 mg of quercetin twice a day for one month provided significant symptomatic improvement in men’s prostate health. Urology 1999; 54(6):960-63.

Urology 2010 Jun; 75(6): 1249-53 - Quercetin use was associated with an increase in beneficial prostate health.

Randomized study in Molecular and Cellular Biochemistry reported that quercetin was able to positively affect the activity of specific enzymes related to prostate health. Mol Cell Biochem 2010 Nov; 344(1-2): 173-84.

The International Journal of Antimicrobial Agents reported on a prospective, randomized study in which 89.6 percent of men who received a combined herbal formula of saw palmetto, stinging nettle, quercetin and curcumin showed significant increase in prostate health after the trial. Int J Antimicrob Agents 2009 Jun; 33(6): 549-53

Beta-sitosterol (Plant Sterols) (65mg): Beta-sitosterol appears to affect the activity of the enzyme 5-alpha-reductase, which in turn may inhibit the production of dihydrotestosterone (DHT), which in turn helps promote proper prostate size and urinary tract health. Studies have shown consistent benefits from 65 mg Prost-P10x dosage in men:

Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol. The authors demonstrated an increase in maximum urine flow rate from a baseline of 9.9 mL/second to 15.2 mL/second, as well as a decrease in mean residual urinary volume. Lancet 1995; 345:1529-1532.A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol).The authors concluded that beta-sitosterol is an effective option in support of prostate health. Br J Urol 1997; 80:427-432.

A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol).The authors concluded that beta-sitosterol is an effective option in support of prostate health. Br J Urol 1997; 80:427-432

Green Tea Extract (leaf, 45% EGCG) (500mg): Green tea provides support for prostate health and normal prostate size. Green tea has also been shown in studies to regulate DHT production and hormones that influence prostate volume. The beneficial effects of taking green tea have been shown to increase with higher levels of green tea/EGCG dosage. Prost-P10x green tea extract contains 500 mg of green tea extract combining 375 mg of catechins (75%) and 450 mg (90%) total polyphenols.

International Journal of Urology reported on green tea studies showing improvements in prostate health. (Lee 2005) Int J Urol 2005 Apr; 12(4): 383-89

Numerous International Journals of Urology, Toxicology and Applied Pharmacology have reported on the effect of green tea on prostate health, normal prostate volume and the regulation of normal hormonal and enzyme activity involved in prostate and urinary health.

Vitamin D-3 (1000IU): Increasing supplemental D-3 intake is associated with a trend of promoting overall prostate health. Vitamin D is widely recognized as being deficient at appropriate levels for prostate and general health which is why Prost-P10x delivers 1000 IU in each daily dosage pack.

3,3-Diindolylmethane (DIM) (100mg): As men age, they experience a decline in testosterone and, in many cases, increases in estrogen levels. The result is a testosterone/ estrogen imbalance that emerging research suggest may impact overall prostate health. Unique to Prost-P10x in this formulation, DIM naturally supports the testosterone/estrogen balance as well as promoting sexual energy and normal prostate size.

Cranberry (Vaccinum macrocapron, fruit) (500mg): Cranberry provides natural support for urinary tract health as well as providing prostate health support. In 2004, France became the first country to approve a health claim for the American cranberry for urinary tract health. A powder based cranberry supplementation at 500 mg can provide significant improvement in prostate health clinical scores based on reported studies:

The British Journal of Nutrition reported cranberries may help support prostate health as well as a reduction in C-reactive protein levels. Vidlar A et al. The effectiveness of dried cranberries (Vaccinium macrocarpon) in men in supporting prostate health. Br J Nutr 2010 Oct; 104(8): 1181-89

British Journal of Nutrition in the same article also reported on statistically significant improvement in Prostate Health Scores, quality of life and urination factors (e.g., rate of urine flow, average flow, total volume, post-void residual urine volume). Br J Nutr 2010 Oct; 104(8): 1181-89

The Journal of Infections and Chemotherapy reported on a study showing the beneficial effects of cranberry on prostate health. Kim SH et al. Do J Infect Chemother 2010 Nov 2

Stinging Nettle (root) (240mg): Stinging Nettle Root may help with the management of urinary tract and volume related to an aging prostate particularly when used with the saw palmetto and quercetin combination in Prost-P10x. The Nettle root provides prostate and urinary tract support and potentially can naturally interact with the binding of DHT providing a further mechanism of action for supporting prostate health.

Six-month, double-blind, placebo-controlled, randomized comparative trial on the effectiveness of stinging nettle on prostate health. 81 percent of men reported an improvement in lower urinary tract health J Herb Pharmacother 2005; 5(4):1-11

Published report in Urologe. Randomized, double-blind, placebo-controlled multicenter study in men reported improved prostate and urinary tract health. Schneider T, Rubben H.. Urologe A 2004 Mar; 43(3): 302-6

The International Journal of Antimicrobial Agents reported on a prospective, randomized study in which 89.6 percent of men who received a combined herbal formula of saw palmetto, stinging nettle (root), quercetin and curcumin had no symptoms of prostatitis after the trial. Int J Antimicrob Agents 2009 Jun; 33(6): 549-5

Pygeum africanum (bark) (CITES certified for sustainable farming practices) (100mg): Pygeum is an herbal remedy derived from the bark of the Pygeum africanum tree that has been used since ancient times to promote bladder health. The major active components of the bark are fat-soluble sterols (phytosterols) and fatty acids that can inhibit the production of DHT (dihydrotestosterone), a hormone that is related to prostate health. Pygeum also may reduce the number of receptor sites where DHT can attach to cells. Numerous studies have supported the use of Pygeum in the management of prostate health:

Journal of Urology reported on a study where the authors concluded that the therapeutic effect of Pygeum africanum may be due at least in part to the inhibition of growth factors responsible for maintaining prostate health. J Urol 1997; 157:2381-87

CITES certified: Ingredients Sourced from Sustainable Plantations.

Current Medical Research and Opinion reported on a study in which the authors concluded that under conditions of daily practice, Pygeum africanum extract induces significant improvement in prostate health and uroflowmetry parameters. Breza J et al.. Curr Med Res Opin 1998; 14(3):127-39.

Zinc (as Zinc Citrate) (15mg): Zinc is known to promote proper sexual function as well as support prostate health. The mineral is also a key player in the body's DNA-damage repair process.

Warning

Unlike Prost-P10x, some prostate supplements are not developed for clinical use and simply do not provide the necessary levels or specific combinations of ingredients that have been shown to be effective in the studies OR they contain ingredients that are misleading and have not been subject to clinical trials.

Prost-P10x combines the required ingredients that have been shown to have a therapeutic effect in research studies in a convenient, once a day packet using our CapliqueTM, all natural capsules.

Prost-P10x also combines organic, natural and clinically researched ingredients without major side effects.

*These statements have not been evaluated by the Food and Drug Administration and are for informational purposes only. They should not be considered medical advice. Always consult a doctor for medical advice. This product is not intended to diagnose, treat, cure, or prevent any disease. Prost-P10x is a registered trademark of Prostate Research Labs, LLC. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Individual results may vary. Citations of studies and research in no way implies any reference to the efficacy or results to be obtained through the use of Prost-P10x. Copyright © 2011 Prostate Research Labs, LLC. Use of this website constitutes acceptance of the Prostate Research Labs, LLC Terms of Use and Privacy Policy. Medical Disclaimer. California Prop. 65 Warning. Sitemap.